SCUTELLARIN INCREASES CISPLATIN-INDUCED APOPTOSIS AND AUTOPHAGY TO OVERCOME CISPLATIN RESISTANCE IN NON-SMALL CELL LUNG CANCER VIA ERK/P53 AND C-MET/AKT SIGNALING PATHWAYS

Cisplatin, as the first-line anti-tumor agent, is widely used for treatment of a variety of malignancies including non-small cell lung cancer (NSCLC).However, the acquired resistance has been a major obstacle for the clinical application.Scutellarin is Disk a active flavone extracted from Erigeron breviscapus Hand-Mazz that has been shown to exhibi

Objective: Sofa Table To determine the epidemiology and clinicopathological pattern of malignant tuours in the adolescence and young adults (AYAs) age groups.Study Design: Cross sectional study.Place and Duration: The study was based on analysis of ten years data of tumor registry (2009-2018), at the Armed Forces Institute of Pathology, Rawalpindi,

Objective: This study aimed to explore the effective method of high-oxygen modified atmosphere packaging for fresh cutting Aralia elata Seem.Methods: In order to explore the effects of high oxygen regulated packaging treatment on the sensory quality and physiological changes of fresh cutting A.elata, different combinations of high oxygen regulated

This work presents the guidance on the results of the development of a laser doping technique and the creation of diode structures based on Cd(Zn)Te semiconductors, due to its attractive physical characteristics.The elements of this compound have relatively large atomic numbers, a significant cross section for photoelectric absorption, a sufficient

A pot experiment was carried out to study the impacts of water stress upon physiological and biochemical properties as well as seed yield and components yield of Alyssum homolocarpum.The factors taken into consideration included water stress (80%), the capacity of field (60%) as well as field capacity (40%) within three stages of growth, stem elong